CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.750 | Elongin C; Chain C, domain 1 |
|
1.10.750.20 | SOCS box |
Domain Context
CATH Clusters
| Superfamily | SOCS box |
| Functional Family | Suppressor of cytokine signaling 1 |
Enzyme Information
UniProtKB Entries (3)
| C0LEJ4 |
C0LEJ4_XENLA
Xenopus laevis
Suppressor of cytokine signaling
|
| Q00560 |
IL6RB_MOUSE
Mus musculus
Interleukin-6 receptor subunit beta
|
| Q15369 |
ELOC_HUMAN
Homo sapiens
Elongin-C
|
PDB Structure
| PDB | 6C5X |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The molecular basis of JAK/STAT inhibition by SOCS1.
Nat Commun
|
