CATH Domain 6ascB01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.21	Purple Acid Phosphatase; chain A, domain 2
	3.60.21.10	Metallo-dependent phosphatases

Domain Context

CATH Clusters

Superfamily	3.60.21.10
Functional Family	DNA double-strand break repair protein Mre11

Enzyme Information

UniProtKB Entries (1)

Q9X1X0_THEMA

Thermotoga maritima MSB8

Nuclease SbcCD subunit D

PDB Structure

PDB	6ASC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Targeting Allostery with Avatars to Design Inhibitors Assessed by Cell Activity: Dissecting MRE11 Endo- and Exonuclease Activities. Moiani, D., Ronato, D.A., Brosey, C.A., Arvai, A.S., Syed, A., Masson, J.Y., Petricci, E., Tainer, J.A. Meth. Enzymol.