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1 keywords

CATH Domain 5yltA02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.170 Beta Complex
Topology 2.170.270 Beta-clip-like
Homologous Superfamily 2.170.270.10 SET domain

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase SETD7

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8WTS6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8WTS6
SETD7_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD7

PDB Structure

PDB 5YLT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.
Hirano, T., Fujiwara, T., Niwa, H., Hirano, M., Ohira, K., Okazaki, Y., Sato, S., Umehara, T., Maemoto, Y., Ito, A., Yoshida, M., Kagechika, H.
ChemMedChem
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