CATH Domain 5y95A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1160	Paired amphipathic helix 2 (pah2 repeat)
	1.20.1160.11	Paired amphipathic helix

Domain Context

CATH Clusters

Superfamily	Paired amphipathic helix
Functional Family	Paired amphipathic helix protein Sin3

Enzyme Information

UniProtKB Entries (1)

SIN3B_MOUSE

Mus musculus

Paired amphipathic helix protein Sin3b

PDB Structure

PDB	5Y95
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models. Ueda, H., Kurita, J.I., Neyama, H., Hirao, Y., Kouji, H., Mishina, T., Kasai, M., Nakano, H., Yoshimori, A., Nishimura, Y. Bioorg. Med. Chem. Lett.