CATH Domain 5waua00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.210	Cytochrome C Oxidase; Chain A
	1.20.210.10	Cytochrome c oxidase-like, subunit I domain

Domain Context

CATH Clusters

Superfamily	Cytochrome c oxidase-like, subunit I domain
Functional Family	Cytochrome c oxidase subunit 1

Enzyme Information

1.9.3.1

Cytochrome-c oxidase.

based on mapping to UniProt P00396

4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.

-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (1)

P07471

CX6A2_BOVIN

Bos taurus

Cytochrome c oxidase subunit 6A2, mitochondrial

PDB Structure

PDB	5WAU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature. Ishigami, I., Zatsepin, N.A., Hikita, M., Conrad, C.E., Nelson, G., Coe, J.D., Basu, S., Grant, T.D., Seaberg, M.H., Sierra, R.G., Hunter, M.S., Fromme, P., Fromme, R., Yeh, S.R., Rousseau, D.L. Proc. Natl. Acad. Sci. U.S.A.