CATH Domain 5wa1A00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.280	alix/aip1 like domains

Domain Context

CATH Clusters

Superfamily	alix/aip1 like domains
Functional Family	programmed cell death 6-interacting protein-like isoform X1

Enzyme Information

UniProtKB Entries (1)

PDC6I_HUMAN

Homo sapiens

Programmed cell death 6-interacting protein

PDB Structure

PDB	5WA1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability. Sadler, J.B.A., Wenzel, D.M., Williams, L.K., Guindo-Martinez, M., Alam, S.L., Mercader, J.M., Torrents, D., Ullman, K.S., Sundquist, W.I., Martin-Serrano, J. Proc. Natl. Acad. Sci. U.S.A.