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1 keywords

CATH Domain 5vklA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.505 SHC Adaptor Protein
Homologous Superfamily 3.30.505.10 SH2 domain

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Transcription elongation factor SPT6

Enzyme Information

UniProtKB Entries (1)

P23615
SPT6_YEAST
Saccharomyces cerevisiae S288C
Transcription elongation factor SPT6

PDB Structure

PDB 5VKL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Sdano, M.A., Fulcher, J.M., Palani, S., Chandrasekharan, M.B., Parnell, T.J., Whitby, F.G., Formosa, T., Hill, C.P.
Elife
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