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1 keywords

CATH Domain 5vacA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.170 Beta Complex
Topology 2.170.270 Beta-clip-like
Homologous Superfamily 2.170.270.10 SET domain

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase ATXR5

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt B9RU15
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (2)

B9RU15
ATXR5_RICCO
Ricinus communis
Probable Histone-lysine N-methyltransferase ATXR5
Q71DI3
H32_HUMAN
Homo sapiens
Histone H3.2

PDB Structure

PDB 5VAC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis for the methylation specificity of ATXR5 for histone H3.
Bergamin, E., Sarvan, S., Malette, J., Eram, M.S., Yeung, S., Mongeon, V., Joshi, M., Brunzelle, J.S., Michaels, S.D., Blais, A., Vedadi, M., Couture, J.F.
Nucleic Acids Res.
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