CATH Domain 5v84D00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Cat eye syndrome critical region protein 2

Enzyme Information

UniProtKB Entries (1)

CECR2_HUMAN

Homo sapiens

Cat eye syndrome critical region protein 2

PDB Structure

PDB	5V84
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2). Crawford, T.D., Audia, J.E., Bellon, S., Burdick, D.J., Bommi-Reddy, A., Cote, A., Cummings, R.T., Duplessis, M., Flynn, E.M., Hewitt, M., Huang, H.R., Jayaram, H., Jiang, Y., Joshi, S., Kiefer, J.R., Murray, J., Nasveschuk, C.G., Neiss, A., Pardo, E., Romero, F.A., Sandy, P., Sims, R.J., Tang, Y., Taylor, A.M., Tsui, V., Wang, J., Wang, S., Wang, Y., Xu, Z., Zawadzke, L., Zhu, X., Albrecht, B.K., Magnuson, S.R., Cochran, A.G. ACS Med Chem Lett