CATH Domain 5nu5B00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.920	Histone Acetyltransferase; Chain A
	1.20.920.10	Bromodomain-like

Domain Context

CATH Clusters

Superfamily	Bromodomain-like
Functional Family	Histone acetyltransferase p300

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q09472 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q09472

UniProtKB Entries (1)

EP300_HUMAN

Homo sapiens

Histone acetyltransferase p300

PDB Structure

PDB	5NU5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles. Hugle, M., Lucas, X., Ostrovskyi, D., Regenass, P., Gerhardt, S., Einsle, O., Hau, M., Jung, M., Breit, B., Gunther, S., Wohlwend, D. Angew. Chem. Int. Ed. Engl.