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1 keywords

CATH Domain 5mr0F01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.470 D-amino Acid Aminotransferase; Chain A, domain 1
Homologous Superfamily 3.30.470.10 Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain

Domain Context

CATH Clusters

Superfamily 3.30.470.10
Functional Family Branched-chain-amino-acid aminotransferase

Enzyme Information

2.6.1.42
Branched-chain-amino-acid transaminase.
based on mapping to UniProt O29329
L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

UniProtKB Entries (1)

O29329
ILVE_ARCFU
Archaeoglobus fulgidus DSM 4304
Putative branched-chain-amino-acid aminotransferase

PDB Structure

PDB 5MR0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Thermostable Branched-Chain Amino Acid Transaminases From the ArchaeaGeoglobus acetivoransandArchaeoglobus fulgidus: Biochemical and Structural Characterization.
Isupov, M.N., Boyko, K.M., Sutter, J.M., James, P., Sayer, C., Schmidt, M., Schonheit, P., Nikolaeva, A.Y., Stekhanova, T.N., Mardanov, A.V., Ravin, N.V., Bezsudnova, E.Y., Popov, V.O., Littlechild, J.A.
Front Bioeng Biotechnol
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