CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 3 | Alpha Beta | 
|   | 3.30 | 2-Layer Sandwich | 
|   | 3.30.1490 | Dna Ligase; domain 1 | 
|   | 3.30.1490.20 | ATP-grasp fold, A domain | 
Domain Context
CATH Clusters
| Superfamily | ATP-grasp fold, A domain | 
| Functional Family | 
Enzyme Information
UniProtKB Entries (3)
| E1BQ43 | E1BQ43_CHICK Gallus gallus Uncharacterized protein | 
| P63043 | STMN4_RAT Rattus norvegicus Stathmin-4 | 
| Q6B856 | TBB2B_BOVIN Bos taurus Tubulin beta-2B chain | 
PDB Structure
| PDB | 5M8D | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | |
| Primary Citation | Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun | 
