CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 3 | Alpha Beta | 
|   | 3.40 | 3-Layer(aba) Sandwich | 
|   | 3.40.50 | Rossmann fold | 
|   | 3.40.50.1440 | Tubulin/FtsZ, GTPase domain | 
Domain Context
CATH Clusters
| Superfamily | Tubulin/FtsZ, GTPase domain | 
| Functional Family | Tubulin beta chain | 
Enzyme Information
UniProtKB Entries (3)
| E1BQ43 | E1BQ43_CHICK Gallus gallus Uncharacterized protein | 
| P63043 | STMN4_RAT Rattus norvegicus Stathmin-4 | 
| P81947 | TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain | 
PDB Structure
| PDB | 5M7G | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | |
| Primary Citation | Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun | 
