CATH Domain 5lkxA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.110	Cysteine Rich Protein
	2.10.110.40	CREB-binding protein/p300 RING domain

Domain Context

CATH Clusters

Superfamily	2.10.110.40
Functional Family	E1A binding protein p300

Enzyme Information

2.3.1.48	Histone acetyltransferase. based on mapping to UniProt Q09472 Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. -!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-	Transferring groups other than amino-acyl groups. based on mapping to UniProt Q09472

UniProtKB Entries (1)

EP300_HUMAN

Homo sapiens

Histone acetyltransferase p300

PDB Structure

PDB	5LKX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of p300 in complex with acyl-CoA variants. Kaczmarska, Z., Ortega, E., Goudarzi, A., Huang, H., Kim, S., Marquez, J.A., Zhao, Y., Khochbin, S., Panne, D. Nat. Chem. Biol.