CATH Domain 5lguB00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.58	Methane Monooxygenase Hydroxylase; Chain G, domain 1
	1.20.58.1880

Domain Context

CATH Clusters

Superfamily	1.20.58.1880
Functional Family	REST corepressor 1

Enzyme Information

UniProtKB Entries (1)

KDM1A_HUMAN

Homo sapiens

Lysine-specific histone demethylase 1A

PDB Structure

PDB	5LGU
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship. Vianello, P., Sartori, L., Amigoni, F., Cappa, A., Faga, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiro, P., Villa, M., Botrugno, O.A., Dessanti, P., Minucci, S., Vultaggio, S., Zagarri, E., Varasi, M., Mercurio, C. J. Med. Chem.