CATH Classification

Domain Context

CATH Clusters

Superfamily Polyketide synthase dehydratase
Functional Family Sterigmatocystin biosynthesis polyketide synthase

Enzyme Information

2.3.1.221
Noranthrone synthase.
based on mapping to UniProt Q12053
7 malonyl-CoA + hexanoyl-[acyl-carrier protein] = 7 CoA + norsolorinate anthrone + [acyl-carrier protein] + 7 CO(2) + 2 H(2)O.
-!- A multi-domain polyketide synthase involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus. -!- The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by a dedicated fungal fatty acid synthase.

UniProtKB Entries (1)

Q12053
AFLC_ASPPU
Aspergillus parasiticus SU-1
Norsolorinic acid synthase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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