CATH Domain 5jzxD03

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.78	Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 1
	3.90.78.10	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

Superfamily	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
Functional Family

1.3.1.98

UDP-N-acetylmuramate dehydrogenase.

based on mapping to UniProt P9WJL9

UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.

-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

MURB_MYCTU

Mycobacterium tuberculosis H37Rv

UDP-N-acetylenolpyruvoylglucosamine reductase

PDB	5JZX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis Eniyan, K., Dharavath, S., Vijayan, R., Bajpai, U., Gourinath, S. Biochim. Biophys. Acta