CATH Domain 5js8A01

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Guanine nucleotide-binding protein G(k) subunit alpha

Enzyme Information

UniProtKB Entries (1)

GNAI1_HUMAN

Homo sapiens

Guanine nucleotide-binding protein G(i) subunit alpha-1

PDB Structure

PDB	5JS8
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding. Goricanec, D., Stehle, R., Egloff, P., Grigoriu, S., Pluckthun, A., Wagner, G., Hagn, F. Proc.Natl.Acad.Sci.USA