CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P45481
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

P04637
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53
P45481
CBP_MOUSE
Mus musculus
CREB-binding protein

PDB Structure

PDB 5HP0
External Links
Method SOLUTION NMR
Organism
Primary Citation
Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Krois, A.S., Ferreon, J.C., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.
Proc.Natl.Acad.Sci.USA
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