CATH Classification
| Level | CATH Code | Description | 
|---|---|---|
|   | 2 | Mainly Beta | 
|   | 2.10 | Ribbon | 
|   | 2.10.90 | Cystine Knot Cytokines, subunit B | 
|   | 2.10.90.10 | Cystine-knot cytokines | 
Domain Context
CATH Clusters
| Superfamily | Cystine-knot cytokines | 
| Functional Family | Gremlin | 
Enzyme Information
UniProtKB Entries (2)
| O88273 | GREM2_MOUSE Mus musculus Gremlin-2 | 
| P43026 | GDF5_HUMAN Homo sapiens Growth/differentiation factor 5 | 
PDB Structure
| PDB | 5HK5 | 
| External Links | |
| Method | X-RAY DIFFRACTION | 
| Organism | |
| Primary Citation | Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism. Cell Rep | 
