CATH Domain 5f0fA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.357	Tetracycline Repressor; domain 2
	1.10.357.10	Tetracycline Repressor, domain 2

Domain Context

CATH Clusters

Superfamily	Tetracycline Repressor, domain 2
Functional Family	HTH-type transcriptional regulator EthR

Enzyme Information

UniProtKB Entries (1)

ETHR_MYCTO

Mycobacterium tuberculosis CDC1551

HTH-type transcriptional regulator EthR

PDB Structure

PDB	5F0F
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. Nikiforov, P.O., Surade, S., Blaszczyk, M., Delorme, V., Brodin, P., Baulard, A.R., Blundell, T.L., Abell, C. Org.Biomol.Chem.