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1 keywords

CATH Domain 5ewmD01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2300 Response regulator

Domain Context

CATH Clusters

Superfamily 3.40.50.2300
Functional Family Glutamate receptor ionotropic, NMDA 2B, putative

Enzyme Information

UniProtKB Entries (2)

Q13224
NMDE2_HUMAN
Homo sapiens
Glutamate receptor ionotropic, NMDA 2B
A0A1L8F5J9
NMDZ1_XENLA
Xenopus laevis
Glutamate receptor ionotropic, NMDA 1

PDB Structure

PDB 5EWM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Novel Binding Mode Reveals Two Distinct Classes of NMDA Receptor GluN2B-selective Antagonists.
Stroebel, D., Buhl, D.L., Knafels, J.D., Chanda, P.K., Green, M., Sciabola, S., Mony, L., Paoletti, P., Pandit, J.
Mol.Pharmacol.
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