CATH Domain 5eqiA00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1250	Growth Hormone; Chain: A;
	1.20.1250.20	MFS general substrate transporter like domains

Domain Context

CATH Clusters

Superfamily	MFS general substrate transporter like domains
Functional Family	Solute carrier family 2, facilitated glucose transporter member 1

Enzyme Information

UniProtKB Entries (1)

GTR1_HUMAN

Homo sapiens

Solute carrier family 2, facilitated glucose transporter member 1

PDB Structure

PDB	5EQI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides. Kapoor, K., Finer-Moore, J.S., Pedersen, B.P., Caboni, L., Waight, A., Hillig, R.C., Bringmann, P., Heisler, I., Muller, T., Siebeneicher, H., Stroud, R.M. Proc.Natl.Acad.Sci.USA