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CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.287.70
Functional Family

Enzyme Information

UniProtKB Entries (2)

A8EVM5
A8EVM5_ARCB4
Arcobacter butzleri RM4018
Ion transport protein
Q15858
SCN9A_HUMAN
Homo sapiens
Sodium channel protein type 9 subunit alpha

PDB Structure

PDB 5EK0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist.
Ahuja, S., Mukund, S., Deng, L., Khakh, K., Chang, E., Ho, H., Shriver, S., Young, C., Lin, S., Johnson, J.P., Wu, P., Li, J., Coons, M., Tam, C., Brillantes, B., Sampang, H., Mortara, K., Bowman, K.K., Clark, K.R., Estevez, A., Xie, Z., Verschoof, H., Grimwood, M., Dehnhardt, C., Andrez, J.C., Focken, T., Sutherlin, D.P., Safina, B.S., Starovasnik, M.A., Ortwine, D.F., Franke, Y., Cohen, C.J., Hackos, D.H., Koth, C.M., Payandeh, J.
Science
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