CATH Classification
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase, accessory domain (PIK) |
| Functional Family | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit |
Enzyme Information
| 2.7.1.153 |
Phosphatidylinositol-4,5-bisphosphate 3-kinase.
based on mapping to UniProt O00329
ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate.
-!- This enzyme also catalyzes the phosphorylation of PtdIns4P to PtdIns(3,4)P(2), and of PtdIns to PtdIns3P.
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UniProtKB Entries (2)
| O00329 |
PK3CD_HUMAN
Homo sapiens
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
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| P23727 |
P85A_BOVIN
Bos taurus
Phosphatidylinositol 3-kinase regulatory subunit alpha
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PDB Structure
| PDB | |
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| Primary Citation |
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