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1 keywords

CATH Domain 5d7nA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1600 SIR2/SIRT2 'Small Domain'
Homologous Superfamily 3.30.1600.10 SIR2/SIRT2 'Small Domain'

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family NAD-dependent deacetylase sirtuin-3, mitochondrial

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q9NTG7

UniProtKB Entries (1)

Q9NTG7
SIR3_HUMAN
Homo sapiens
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

PDB Structure

PDB 5D7N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking.
Rumpf, T., Gerhardt, S., Einsle, O., Jung, M.
Acta Crystallogr.,Sect.F
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