CATH Domain 4x8yB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.120	Flavocytochrome B2; Chain A, domain 1
	3.10.120.10	Cytochrome b5-like heme/steroid binding domain

Domain Context

CATH Clusters

Superfamily	Cytochrome b5-like heme/steroid binding domain
Functional Family	membrane-associated progesterone receptor component 1

Enzyme Information

UniProtKB Entries (1)

PGRC1_HUMAN

Homo sapiens

Membrane-associated progesterone receptor component 1

PDB Structure

PDB	4X8Y
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance Kabe, Y., Nakane, T., Koike, I., Yamamoto, T., Sugiura, Y., Harada, E., Sugase, K., Shimamura, T., Ohmura, M., Muraoka, K., Yamamoto, A., Uchida, T., Iwata, S., Yamaguchi, Y., Krayukhina, E., Noda, M., Handa, H., Ishimori, K., Uchiyama, S., Kobayashi, T., Suematsu, M. Nat Commun