CATH Domain 4wlfC02

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.110	L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
	3.90.110.10	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family	Malate dehydrogenase

1.1.1.37

Malate dehydrogenase.

based on mapping to UniProt P40926

(S)-malate + NAD(+) = oxaloacetate + NADH.

-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

MDHM_HUMAN

Homo sapiens

Malate dehydrogenase, mitochondrial

PDB	4WLF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of L-malate bound MDH2 Eo, Y.M., Han, B.G., Ahn, H.C. To Be Published