CATH Domain 4qxoA01

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.5	Single alpha-helices involved in coiled-coils or other helix-helix interfaces
	1.20.5.5200

Domain Context

CATH Clusters

Superfamily	1.20.5.5200
Functional Family	Stimulator of interferon genes protein

Enzyme Information

UniProtKB Entries (1)

STING_HUMAN

Homo sapiens

Stimulator of interferon genes protein

PDB Structure

PDB	4QXO
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA. Gao, P., Zillinger, T., Wang, W., Ascano, M., Dai, P., Hartmann, G., Tuschl, T., Deng, L., Barchet, W., Patel, D.J. Cell Rep