×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4pywA02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.39 Alpha-1-antitrypsin; domain 1
Homologous Superfamily 2.30.39.10 Alpha-1-antitrypsin, domain 1

Domain Context

CATH Clusters

Superfamily Alpha-1-antitrypsin, domain 1
Functional Family alpha-1-antitrypsin isoform X1

Enzyme Information

UniProtKB Entries (1)

P01009
A1AT_HUMAN
Homo sapiens
Alpha-1-antitrypsin

PDB Structure

PDB 4PYW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An integrative approach combining ion mobility mass spectrometry, X-ray crystallography and NMR spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Nyon, M.P., Prentice, T., Day, J., Kirkpatrick, J., Sivalingam, G.N., Levy, G., Haq, I., Irving, J.A., Lomas, D.A., Christodoulou, J., Gooptu, B., Thalassinos, K.
Protein Sci.
CATH-Gene3D is a Global Biodata Core Resource Learn more...