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1 keywords

CATH Domain 4mucB02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.10 Ribbon
Topology 2.10.70 Complement Module; domain 1
Homologous Superfamily 2.10.70.10 Complement Module, domain 1

Domain Context

CATH Clusters

Superfamily Complement Module, domain 1
Functional Family Complement inhibitory factor H

Enzyme Information

UniProtKB Entries (1)

Q03591
FHR1_HUMAN
Homo sapiens
Complement factor H-related protein 1

PDB Structure

PDB 4MUC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease.
Bhattacharjee, A., Reuter, S., Trojnar, E., Kolodziejczyk, R., Seeberger, H., Hyvarinen, S., Uzonyi, B., Szilagyi, A., Prohaszka, Z., Goldman, A., Jozsi, M., Jokiranta, T.S.
J.Biol.Chem.
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