CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.230 | Ribosomal Protein S5; domain 2 |
|
3.30.230.40 | Imidazole glycerol phosphate dehydratase; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Imidazole glycerol phosphate dehydratase; domain 1 |
| Functional Family | Imidazoleglycerol-phosphate dehydratase HisB |
Enzyme Information
| 4.2.1.19 |
Imidazoleglycerol-phosphate dehydratase.
based on mapping to UniProt P9WML9
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2- oxopropyl phosphate + H(2)O.
|
UniProtKB Entries (1)
| P9WML9 |
HIS7_MYCTU
Mycobacterium tuberculosis H37Rv
Imidazoleglycerol-phosphate dehydratase
|
PDB Structure
| PDB | 4GQU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the native, substrate-
bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase
Acta Crystallogr.,Sect.D
|
