CATH Domain 4gewA02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.10	Deoxyribonuclease I; Chain A
	3.60.10.10	Endonuclease/exonuclease/phosphatase

Domain Context

CATH Clusters

Superfamily	Endonuclease/exonuclease/phosphatase
Functional Family	Tdpt-1

Enzyme Information

3.1.4.-

Phosphoric diester hydrolases.

based on mapping to UniProt Q9XWG3

UniProtKB Entries (1)

TYDP2_CAEEL

Caenorhabditis elegans

5'-tyrosyl-DNA phosphodiesterase

PDB Structure

PDB	4GEW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2. Shi, K., Kurahashi, K., Gao, R., Tsutakawa, S.E., Tainer, J.A., Pommier, Y., Aihara, H. Nat.Struct.Mol.Biol.