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1 keywords

CATH Domain 4fb8A02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.226 2-enoyl-CoA Hydratase; Chain A, domain 1
Homologous Superfamily 3.90.226.10 2-enoyl-CoA Hydratase; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily 2-enoyl-CoA Hydratase; Chain A, domain 1
Functional Family Propionyl-CoA carboxylase subunit beta 6

Enzyme Information

6.4.1.3
Propionyl-CoA carboxylase.
based on mapping to UniProt P9WQH4
ATP + propanoyl-CoA + HCO(3)(-) = ADP + phosphate + (S)-methylmalonyl- CoA.
-!- Also carboxylates butanoyl-CoA and catalyzes transcarboxylation.

UniProtKB Entries (1)

P9WQH4
PCC6_MYCTO
Mycobacterium tuberculosis CDC1551
Probable propionyl-CoA carboxylase beta chain 6

PDB Structure

PDB 4FB8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure, Activity, and Inhibition of the Carboxyltransferase beta-Subunit of Acetyl Coenzyme A Carboxylase (AccD6) from Mycobacterium tuberculosis.
Reddy, M.C., Breda, A., Bruning, J.B., Sherekar, M., Valluru, S., Thurman, C., Ehrenfeld, H., Sacchettini, J.C.
Antimicrob.Agents Chemother.
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