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1 keywords

CATH Domain 4eyrB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

Q000H7
Q000H7_9HIV1
Human immunodeficiency virus 1
Pol protein

PDB Structure

PDB 4EYR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex.
Liu, Z., Yedidi, R.S., Wang, Y., Dewdney, T.G., Reiter, S.J., Brunzelle, J.S., Kovari, I.A., Kovari, L.C.
Biochem.Biophys.Res.Commun.
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