CATH Domain 4cl1C02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.20	Single Sheet
	2.20.25	N-terminal domain of TfIIb
	2.20.25.220	Hepatitis C virus NS5A, 1B domain

Domain Context

CATH Clusters

Superfamily	Hepatitis C virus NS5A, 1B domain
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

K4KA16_9HEPC

Hepacivirus C

Genome polyprotein

PDB Structure

PDB	4CL1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Crystal Structure of Ns5A Domain 1 from Genotype 1A Reveals New Clues to the Mechanism of Action for Dimeric Hcv Inhibitors. Lambert, S.M., Langley, D.R., Garnett, J.A., Angell, R., Hedgethorne, K., Meanwell, N.A., Matthews, S.J. Protein Sci.