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1 keywords

CATH Domain 4cceA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.80 Glycosidases

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family galactocerebrosidase precursor

Enzyme Information

3.2.1.46
Galactosylceramidase.
based on mapping to UniProt P54818
D-galactosyl-N-acylsphingosine + H(2)O = D-galactose + N-acylsphingosine.
-!- Cf. EC 3.2.1.62.

UniProtKB Entries (1)

P54818
GALC_MOUSE
Mus musculus
Galactocerebrosidase

PDB Structure

PDB 4CCE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Hill, C.H., Graham, S.C., Read, R.J., Deane, J.E.
Proc.Natl.Acad.Sci.USA
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