CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.50 | FAD/NAD(P)-binding domain |
|
3.50.50.60 | FAD/NAD(P)-binding domain |
Domain Context
CATH Clusters
| Superfamily | FAD/NAD(P)-binding domain |
| Functional Family | Thioredoxin reductase |
Enzyme Information
| 1.8.1.9 |
Thioredoxin-disulfide reductase.
based on mapping to UniProt Q25861
Thioredoxin + NADP(+) = thioredoxin disulfide + NADPH.
-!- May be identical to EC 1.8.1.10. -!- Formerly EC 1.6.4.5.
|
UniProtKB Entries (1)
| Q25861 |
TRXR_PLAF5
Plasmodium falciparum FCH-5
Thioredoxin reductase
|
PDB Structure
| PDB | 4B1B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Plasmodium Falciparum Thioredoxin Reductase, a Validated Drug Target.
Biochem.Biophys.Res.Commun.
|
