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1 keywords

CATH Domain 4a0pA02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.120 6 Propeller
Topology 2.120.10 Neuraminidase
Homologous Superfamily 2.120.10.30 TolB, C-terminal domain

Domain Context

CATH Clusters

Superfamily TolB, C-terminal domain
Functional Family Low-density lipoprotein receptor-related protein 6

Enzyme Information

UniProtKB Entries (1)

O75581
LRP6_HUMAN
Homo sapiens
Low-density lipoprotein receptor-related protein 6

PDB Structure

PDB 4A0P
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling.
Chen, S., Bubeck, D., Macdonald, B.T., Liang, W.X., Mao, J.H., Malinauskas, T., Llorca, O., Aricescu, A.R., Siebold, C., He, X., Jones, E.Y.
Dev.Cell
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