CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family cyclin-dependent kinase-like 1 isoform X1

Enzyme Information

2.7.11.22
Cyclin-dependent kinase.
based on mapping to UniProt Q8IVW4
ATP + a protein = ADP + a phosphoprotein.
-!- Activation of cyclin-dependent kinases requires association of the enzyme with a regulatory subunit referred to as a cyclin. -!- It is the sequential activation and inactivation of cyclin-dependent kinases, through the periodic synthesis and destruction of cyclins, that provides the primary means of cell-cycle regulation. -!- Formerly EC 2.7.1.37.

UniProtKB Entries (1)

Q8IVW4
CDKL3_HUMAN
Homo sapiens
Cyclin-dependent kinase-like 3

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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