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1 keywords

CATH Domain 3u78A02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.58 Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homologous Superfamily 1.20.58.1360  

Domain Context

CATH Clusters

Superfamily 1.20.58.1360
Functional Family Lysine-specific demethylase 7A

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q6ZMT4

UniProtKB Entries (1)

Q6ZMT4
KDM7A_HUMAN
Homo sapiens
Lysine-specific demethylase 7A

PDB Structure

PDB 3U78
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An Analog of BIX-01294 Selectively Inhibits a Family of Histone H3 Lysine 9 Jumonji Demethylases.
Upadhyay, A.K., Rotili, D., Han, J.W., Hu, R., Chang, Y., Labella, D., Zhang, X., Yoon, Y.S., Mai, A., Cheng, X.
J.Mol.Biol.
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