CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.600 | Farnesyl Diphosphate Synthase |
|
1.10.600.10 | Farnesyl Diphosphate Synthase |
Domain Context
CATH Clusters
| Superfamily | Farnesyl Diphosphate Synthase |
| Functional Family | Dehydrosqualene synthase |
Enzyme Information
| 2.5.1.96 |
4,4'-diapophytoene synthase.
based on mapping to UniProt A9JQL9
2 (2E,6E)-farnesyl diphosphate = 15-cis-4,4'-diapophytoene + 2 diphosphate.
-!- Typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.
|
UniProtKB Entries (1)
| A9JQL9 |
CRTM_STAAU
Staphylococcus aureus
4,4'-diapophytoene synthase
|
PDB Structure
| PDB | 3TFN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
Chemmedchem
|
