CATH Domain 3sv8A02

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Genome polyprotein

Enzyme Information

UniProtKB Entries (1)

A8DG50_9HEPC

Hepatitis C virus subtype 1a

Genome polyprotein

PDB Structure

PDB	3SV8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Romano, K.P., Ali, A., Aydin, C., Soumana, D., Ozen, A., Deveau, L.M., Silver, C., Cao, H., Newton, A., Petropoulos, C.J., Huang, W., Schiffer, C.A. Plos Pathog.