CATH Domain 3s4yB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10240	Thiamin pyrophosphokinase, catalytic domain

Domain Context

CATH Clusters

Superfamily	Thiamin pyrophosphokinase, catalytic domain
Functional Family	Thiamin pyrophosphokinase 1

Enzyme Information

2.7.6.2

Thiamine diphosphokinase.

based on mapping to UniProt Q9H3S4

ATP + thiamine = AMP + thiamine diphosphate.

UniProtKB Entries (1)

TPK1_HUMAN

Homo sapiens

Thiamin pyrophosphokinase 1

PDB Structure

PDB	3S4Y
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of human thiamin pyrophosphokinase 1 Shen, L., Tempel, W., Tong, Y., Li, Y., Walker, J.R., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Park, H. to be published