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1 keywords

CATH Domain 3qw4C01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase

Enzyme Information

UniProtKB Entries (1)

E9BCQ9
E9BCQ9_LEIDB
Leishmania donovani BPK282A1
Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative

PDB Structure

PDB 3QW4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
French, J.B., Yates, P.A., Soysa, D.R., Boitz, J.M., Carter, N.S., Chang, B., Ullman, B., Ealick, S.E.
J.Biol.Chem.
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