CATH Domain 3ng5B00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.180	Transthyretin/hydroxyisourate hydrolase domain

Domain Context

CATH Clusters

Superfamily	Transthyretin/hydroxyisourate hydrolase domain
Functional Family	Transthyretin

Enzyme Information

UniProtKB Entries (1)

TTHY_HUMAN

Homo sapiens

Transthyretin

PDB Structure

PDB	3NG5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site Miyata, M., Sato, T., Kugimiya, M., Sho, M., Nakamura, T., Ikemizu, S., Chirifu, M., Mizuguchi, M., Nabeshima, Y., Suwa, Y., Morioka, H., Arimori, T., Suico, M.A., Shuto, T., Sako, Y., Momohara, M., Koga, T., Morino-Koga, S., Yamagata, Y., Kai, H. Biochemistry