CATH Domain 3ndaA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.497	Antithrombin; Chain I, domain 2
	3.30.497.10	Antithrombin, subunit I, domain 2

Domain Context

CATH Clusters

Superfamily	Antithrombin, subunit I, domain 2
Functional Family	Putative salivary serpin

Enzyme Information

UniProtKB Entries (1)

Q06B74_IXORI

Ixodes ricinus

Serpin-2

PDB Structure

PDB	3NDA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Chmelar, J., Oliveira, C.J., Rezacova, P., Francischetti, I.M., Kovarova, Z., Pejler, G., Kopacek, P., Ribeiro, J.M., Mares, M., Kopecky, J., Kotsyfakis, M. Blood