×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 3mq3A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.60 4-Layer Sandwich
Topology 3.60.40 Phosphatase 2c; domain 1
Homologous Superfamily 3.60.40.10 PPM-type phosphatase domain

Domain Context

CATH Clusters

Superfamily PPM-type phosphatase domain
Functional Family Pyruvate dehyrogenase phosphatase catalytic subunit 1

Enzyme Information

3.1.3.43
[Pyruvate dehydrogenase (acetyl-transferring)]-phosphatase.
based on mapping to UniProt P35816
[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.
-!- A mitochondrial enzyme associated with EC 1.2.4.1 in the pyruvate dehydrogenase complex.

UniProtKB Entries (1)

P35816
PDP1_BOVIN
Bos taurus
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

PDB Structure

PDB 3MQ3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Catalytic Subunit of Bovine Pyruvate Dehydrogenase Phophatase
Guo, Y., Ernst, S.R., Carroll, D.W., Hackert, M.L.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...