CATH Domain 3lyrA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.3180	Transcription factor COE1, DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Transcription factor COE1, DNA-binding domain
Functional Family	EBF transcription factor 2

Enzyme Information

UniProtKB Entries (1)

COE1_HUMAN

Homo sapiens

Transcription factor COE1

PDB Structure

PDB	3LYR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. Siponen, M.I., Wisniewska, M., Lehtio, L., Johansson, I., Svensson, L., Raszewski, G., Nilsson, L., Sigvardsson, M., Berglund, H. J.Biol.Chem.