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1 keywords

CATH Domain 3lbcD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family N-acetylneuraminate lyase

Enzyme Information

4.1.3.3
N-acetylneuraminate lyase.
based on mapping to UniProt P0A6L4
N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
-!- Also acts on N-glycoloylneuraminate, and on O-acetylated sialic acids, other than 4-O-acetylated derivatives.

UniProtKB Entries (1)

P0A6L4
NANA_ECOLI
Escherichia coli K-12
N-acetylneuraminate lyase

PDB Structure

PDB 3LBC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
Chou, C.-Y., Ko, T.-P., Wu, K.-J., Huang, K.-F., Lin, C.-H., Wong, C.-H., Wang, A.H.-J.
To be Published
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